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Will side effects compound over time
The general principle these definitions reflect is a pharmacokinetic property rather than a dosing instruction: with a half-life of roughly one week, exposure declines gradually rather than abruptly across a shifted or missed interval
Receding or sparse temples
Persistent activation and accumulation of myofibroblasts without resolution of the reparative response underlies the progressive nature of fibrotic reactions in injured tissue [5]
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Hu ML, Rayner CK, Wu KL, Chuah SK, Tai WC, Chou YP, Chiu YC, Chiu KW, Hu TH
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