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Archived from the original on 8 March 2024

None of these studies should be interpreted as recommending GHK-Cu for human use, treatment, or any clinical purpose

Synovial M1 macrophages also promote the synthesis and secretion of proteolytic enzymes, such as matrix metalloproteinases (MMPs) including MMP-1, MMP-3, MMP-13, MMP-9, ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs), and cyclooxygenase-2 (COX-2)