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The SURMOUNT-1 trial (N=2,539), published in the New England Journal of Medicine in 2022 (DOI: 10.1056/NEJMoa2206038), evaluated tirzepatide at 5mg, 10mg, and 15mg weekly doses versus placebo in adults with obesity or overweight
Not all patients are appropriate candidates for peptide therapy
Some users extend to longer periods for chronic conditions or transition to indefinite low-dose maintenance
Within a few hours of the injection, many individuals experience an increase in physical energy, mental clarity, and a greater sense of well-being
Both halves of that sentence matter
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