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Previous research has gathered evidence supporting the hypotheses that healthy aging is an increasing biological noise, a consequence of diffuse proteome oxidation, whereas ARDs appear associated with excessive oxidation of particular susceptible proteins sensitized by mutations predisposing to disease 2
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Berberine, for example, appears to increase GLP-1 secretion through multiple pathways including activation of the TGR5 receptor and modulation of gut microbiota composition
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