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10.1080/10408398.2023.2227262 68 GhaleihaA.MohammadiE.MohammadiM

In summary, the action of valproate in neural systems is complex, with one aspect including downregulation of PKC signaling, which overlaps with symptom amelioration of manic states in animal models, suggesting that modulation of PKC overactivity is a mechanism that is favored by valproate

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Insulin is the key that opens the cells to take in the sugar