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The Sleeping Brain: Harnessing the Power of the Glymphatic System through Lifestyle Choices

However, glycemic control improved markedly, with HbA1C reductions of 2.0-2.5% from baselines typically around 8.0-8.5%

in trial data, this effect appears to be offset by the concurrent GLP-1 and GIP activity, though the precise interplay in humans remains under investigation