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Increased GSH synthesis neutralizes reactive oxygen and nitrogen species and regulates zinc homeostasis promoting neuroprotection after ischemia/reperfusion (162)
Molecules 24 (13), 2481
How PlexusDx Supports a More Personalized Approach PlexusDx's Precision Peptide Genetic Test may help provide context on your individual antioxidant pathway function by examining genetic variants related to glutathione synthesis and metabolism
There are two types of toxic-related effects, intrinsic and idiosyncratic [3, 4]
Abbreviations A: amyloid beta ACh: acetylcholine AD: Alzheimers disease BBB: bloodbrain barrier BDNF: brain-derived neurotrophic factor CIND: cognitive impairment, no dementia CNS: central nervous system ERGO: ergothioneine GABA: -amino butyric acid MCI: mild cognitive impairment mTOR: mammalian target of rapamycin NMDA: N-Methyl-D-aspartate NT5: neurotrophin 4/5 PD: Parkinsons disease References Halliwell B, Cheah IK, Tang RMY (2018) Ergothioneine - a diet-derived antioxidant with therapeutic potential
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