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Comparison of Combinatorial Fragment Spaces and Its Application to Ultralarge Make-on-Demand Compound Catalogs

Because MOTS-c enhances insulin-independent glucose uptake, patients with type 1 diabetes or those using exogenous insulin should be monitored carefully to prevent hypoglycemia, though this theoretical risk has not materialized in clinical reports to date

Administration of ketones after controlled cortical impact injury in young rats reduced lesion volume, attenuated motor and cognitive deficits, reduced cellular apoptotic markers, and improved cerebral ATP levels (Prins et al., 2005

This change in turn enables the USP catalytic domain to efficiently catalyze the deubiquitination reaction [26, 35]

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