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However, stopping abruptly significantly increases the risk of rapid weight regain and appetite rebound compared to a gradual taper

The question at this stage is whether the incremental benefit over 12.5mg justifies the increased side effect burden

Dehydration Risk Reduced appetite on GLP-1 medications often extends to reduced thirst

Choosing between a daily pill and a weekly shot may come down to preference, routine, and whats easiest to stick with long term