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Abnormal sperm morphology and an increase in malondialdehyde (MDA) levels were observed in the 10 mg/kg treatment group, whereas the changes were more pronounced in the 20 mg/kg treatment group, which exhibited a decrease in sperm counts, abnormal sperm morphology, DNA damage, degradation of cellular tubular structures, and elevated serum LH and testosterone levels
Data shown that dysfunction of autophagy lysosome system can affect the clearance of A peptides and tau proteins, two major features of AD (74)
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