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Ten-eleven Translocation (TET) enzymes converts methylcytosine (m 5 C) to hydroxymethylcytosine (hmC), which is not recognized by Dnmt1, it is believed to exclude maintenance methylation allowing for passive demethylation, and it is an intermediate in the active conversion of m 5 C to cytosine (C) 27
Statistics by two-sided unpaired t-tests as indicated or compared to untreated cells ( a-c, e ) or ML162 treated cells ( d, f )
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Crucially, this action is glucose-dependent, meaning it primarily happens when blood sugar levels are high, such as after a meal
Km: c tnh chng vim v lm tng s ti to b mt ca vt thng c hiu qu tt trong iu tr mn, bnh chm
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