If you get side effects like vomiting or diarrhoea while taking Wegovy, you may need to use another form of contraception to prevent pregnancy
External resources STEP 1 Trial: Once-Weekly Semaglutide in Adults with Overweight or Obesity (NEJM) STEP 5 Trial: Two-Year Effects of Semaglutide (Nature Medicine) Semaglutide Effects on Nutritional Metrics Including B12 (PMC) Semaglutide for Overweight and Obesity: A Comprehensive Review (PMC) For researchers serious about optimizing their semaglutide B12 protocol, SeekPeptides offers the most comprehensive resource available, with evidence-based guides, proven protocols, dosing calculators, and a community of thousands who have navigated these exact questions
By restoring essential nutrients, it supports healthy nerve function, red blood cell production, and energy levels, improving overall well-being
The FDA also noted major evidence gaps for subcutaneous, topical, and nasal exposure, so the trial record does not establish safety for those routes
Drug Design, Development and Therapy, 9, 2485-2499
Distal symmetric polyneuropathy: a definition for clinical research: report of the American Academy of Neurology, the American Association of Electrodiagnostic Medicine, and the American Academy of Physical Medicine and Rehabilitation