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Gene Regulation: Downregulates senescence markers like p16 (INK4a) and p21 (Waf1), delaying cellular aging
Macrophages and mast cells clear damaged tissue and cellular debris, while secreting proteins essential for wound contraction and overall tissue healing
Moreover, blood Lys concentration was lower in the groups that received RPM in low CP diets, compared to the negative control groups (low CP without RPM supplementation) supporting the idea that Lys could have been the first-limiting AA for growth instead of Met (Inhuber et al., 2021)
This property is particularly relevant in conditions like Alzheimers disease, where metal ion imbalance contributes to disease progression 9
Evidence for loading protocols remains anecdotal, and many users achieve good results with consistent moderate dosing from day one
H.JiangS.-N.ParkS.-H.TanW.HongS
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