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Clinical trials suggest its generally well-tolerated, but a few key points stand out

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Norris recommends vegan adults 18 to 65 years old should take one of the following regimens: two doses per day of 2 to 3.5 mcg per serving, one dose per day of 25 to 100 mcg per serving, or two doses per week of 1,000 mcg per serving

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The enzyme NNMT normally changes nicotinamide, a form of vitamin B3, by using methyl groups, which lowers nicotinamide adenine dinucleotide (NAD+) levels

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