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In the one human trial studying oral BPC-157 for inflammatory bowel disease, approximately 8% reported mild GI symptoms compared to 6% on placebo (Klicek et al., 2012)

Thyroid concerns arose during drug development due to C-cell hyperplasia and medullary thyroid carcinoma seen in rodent studies

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A randomized, double-blind trial of thymosin beta-4 in 72 patients with chronic venous stasis ulcers showed statistically significant wound closure compared to placebo at 3 months 12