The antibody portion of the ADC mainly targets specific protein receptors found on tumor cells, with the goal of delivering the cytotoxic payload more directly to tumor cells, reducing damage to healthy tissues, and minimizing off-target effects
Findings from published studies suggest possible mechanisms of action including increased collagen synthesis, modulation of inflammatory cytokines, and promotion of angiogenesis
Role in systemic acquired resistance
ARA-290 has demonstrated actual small nerve fiber regrowth in human clinical trials, measured by corneal confocal microscopy
Symptoms include breathing problems, wheezing, swelling in your face, lips, tongue, fast heartbeat, pale, cold skin and feeling dizzy or weak
Neither format is inherently better the right choice depends on your providers clinical recommendation and personal preference