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This product is intended for qualified research professionals conducting scientific investigation in controlled laboratory environments

Eight patients in the metformin group discontinued the study prematurely: 1 patient due to dyspepsia, 2 due to fatigue, 2 due to a lack of perceived efficacy, 2 due to worsening psychiatric symptoms and a consequent change of psychotropic medication, and 1 due to substance abuse

Most patients restart at a low introductory dose when switching GLP-1 medications to limit side effects

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