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Risk-benefit implications With increasing prevalence of GLP-1 agonists in our perioperative population and emerging reports of retained gastric content despite recommended fasting guidelines, a review on the perioperative handling of GLP-1 agonists and assessment of these patients are warranted to balance their cardiometabolic benefits and unquantified risk of catastrophic pulmonary aspiration

These medications have revolutionized weight management, with clinical studies showing patients losing 15-20% of their body weight on average after one year of treatment

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