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However, in their model, proteasome inhibitors blocked CPP extinction when injected following each extinction session but were not efficient on memory consolidation during the learning phase

Mice with inactivating mutations in the gene coding for the enzyme alcohol dehydrogenase 5 (Adh5) and in the gene coding for the factor Fanconi Anaemia Complementation Group D2 (Fancd2) accumulate FA-DNA adducts and present hematopoietic stem cell attrition, which correlates with genome instability in the hematopoietic compartment 9

Nat Commun 16 , 5547 (2025)

10.1074/jbc.M410818200

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