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These reactions can happen regardless of the quality of the supplement if the individual has a specific sensitivity to one of the amino acids or the sulfur component of the molecule

Further, NICE and the BNF says that if there are neurological symptoms present, then every other day injections are the recommended treatment, so all the points you make about B12 being stored and sufficient are not really relevant

This arrangement enabled Pfizer to become the leader in sterile injectable and biosimilar pharmaceuticals around the world

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Allergies and sensitivities may play a role in the development of autoimmune diseases