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As a result, caution is advised when supplementing G

Most studies showing benefits used between 2,000 to 5,000 mg per day

This bypasses the skin barrier that limits topical absorption, allowing higher concentrations to reach the dermis and deeper tissue layers

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Lai YH, Lee MC, Ho GJ et al (2019) Association of low serum L-carnitine levels with peripheral arterial stiffness in patients who undergo kidney transplantation