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Treatment should be discontinued if inadequate response occurs: less than 5% weight loss after 6 months for Wegovy or 12 weeks for Saxenda at maintenance doses
10.1146/annurev.physiol.68.033104.152158 131 KanlayaprasitS.ThongkornS.PanjabudP.JindatipD.HuV
Starting an available medication now probably makes more sense if: Your BMI is 30 (or 27 with complications like diabetes, sleep apnea, or joint pain) and your health would benefit from treatment today not in 2027
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PMC 7979486
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