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A large retrospective analysis of 237,043 patients with hip or knee OA, including 23,000 individuals exposed to GLP-1 agonists for at least 1 year, found that arthroplasty risk at 1 year was reduced by approximately 40% for hip replacement and 25% for knee replacement
The tirzepatide equivalent of this formulation, the tirzepatide glycine B12 compound , follows similar logic but uses a dual GIP/GLP-1 agonist as the base instead
Dosage Overdose Missed a Dose How does this medicine work
Gastrointestinal Risks and Safety Concerns Available evidence indicates that retatrutide may cause several side effects, most commonly affecting the digestive system
Laboratory research record on GLP-1S [PMID: 42278967] PubMed laboratory record discussing GLP-1S in a research context
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