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Future research should investigate long-term outcomes in high-risk populations, direct comparisons between physiological and pharmacological dosages, cost-effectiveness analyses, and adherence metrics to inform optimal strategies for the prevention and management of vitamin B12 deficiency

Additionally, older adults who naturally have a more challenging time absorbing vitamin B12 or those on certain medications that affect B12 absorption may be ideal candidates

J Clin Exp Pharmacol, 9(262), 2161-1459

Tumors : A tumor may cause inflammation in the spinal canal

This position is supported by the NICE Guideline and at the end of 2025 we launched our freely accessible Pernicious Anaemia and B12 Deficiency education programme to the NHS community

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