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In overdosage, satura-tion of the phase II metabolic pathways results in a greater proportion of the drug undergoing bioactiva-tion

It does not independently verify product identity, purity, potency, contamination, or manufacturing quality

Blier P, Ward HE, Tremblay P, Laberge L, Hbert C, Bergeron R

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Similarly, the other incretin hormone, GIP is efficiently cleaved by DPP-4 in vivo (40), and DPP-4 inhibition increases intact GIP levels and enhances its effects (41)

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