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Hair thinning: Can occur with rapid weight loss, usually temporary
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doi: 10.1186/s10086-022-02033-6 23 KhnelH.SeilerM.FeldhoferB.EbrahimianA.MaurerM
Its main physiological roles include stimulating insulin release in a glucose-dependent manner, suppressing glucagon (another hormone that raises blood sugar), slowing gastric emptying, and reducing appetite
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Moreover, several clinical studies show that glycemia improves when doses are increased but with unacceptable rates of gastrointestinal adverse events 16,17,18 , suggesting that maximum benefits from GLP-1R agonism are in fact not realized with current treatments
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