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Yes , for any in vitro biological assay where the reconstituted peptide is added to cell cultures or tissue preparations, matched Bacteriostatic Water vehicle controls at the same final benzyl alcohol concentration as the highest peptide treatment concentration should be included to confirm absence of benzyl alcohol-mediated biological effects on the assay endpoints measured

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TB-500, as supplied by most research vendors, is a short synthetic fragment corresponding to the actin-binding region within that sequence

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A few studies have been done addressing the above issue (Table 2) [51,52,53]