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Xc- inhibitor sulfasalazine sensitizes colorectal cancer to cisplatin by a GSH-dependent mechanism

It is administered by a licensed practitioner via the intramuscular (I.M.) or intravenous (I.V.) route, following the package insert

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Interestingly, the chimeric construct also exhibited reduced protein levels, perhaps suggesting increased degradation of the inactive Rab chimera (Supplementary Fig