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The same mechanism may explain why the risk appears highest in the first year of therapy when metabolic improvements are most rapid and why the signal seems stronger with more potent agents
Independent pharmacokinetic comparison studies are limited
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As a result, many people may have suboptimal levels of this critical antioxidant, leading to increased susceptibility to oxidative stress, chronic inflammation, and a higher risk of chronic diseases
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In addition, necropsy was performed on Day 43 to evaluate biocompatibility and potential local or systemic toxicity
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