depletion of glutathione induces ferroptosis, autophagy, and premature cell senescence in retinal pigment epithelial cells Photothermal-enhanced glutathione depletion and self-sustaining

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Potential concerns include local injection reactions, immune responses to copper, and theoretical risks from unintended growth pathway activation

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This study found that heat hyperalgesia was decreased with TRPV1 antagonism and that TRPV1 expression in large neurons in the trigeminal ganglia was increased