In vitro investigation of Dihexa routinely focuses on organotypic hippocampal slice cultures, primary rodent neuronal cultures, and human induced pluripotent stem cell (iPSC)-derived neurons
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Ref.: Schoenenberger & Monnier, PNAS 1977 + Graf & Kastin, Neurosci Biobehav Rev 1984 Summary of the main publications on cognitive neuropeptides available in our catalogue
It could have to do with effects that are partially mediated by sex hormones or it could have to do with sex differences in immune function. Next steps Mavromatis and colleagues intend to follow patients treated with GLP-1 receptor agonists longer to continue to assess outcomes