Targeted protection of mitochondrial function by nanoparticles Mitochondrial dysfunction is a key pathological mechanism in the process of RIRI, primarily involving abnormalities in the ETC, excessive ROS production, and disruption of mitochondrial membrane structure
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Chen CB, Hsiao YH, Wu T, Hsih MS, Tassaneeyakul W, Jorns TP, Sukasem C, Hsu CN, Su SC, Chang WC, Hui RC, Chu CY, Chen YJ, Wu CY, Hsu CK, Chiu TM, Sun PL, Lee HE, Yang CY, Kao PH, Yang CH, Ho HC, Lin JY, Chang YC, Chen MJ, CW L, Ng CY, Kuo KL, Lin CY, Yang CS, Chen DP, Chang PY, Wu TL, Lin YJ, Weng YC, Kuo TT, Hung SI, Chung WH (2017) Risk and association of HLA with oxcarbazepine-induced cutaneous adverse reactions in Asians
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This timing allows peak tissue levels to coincide with the first sleep cycle when growth hormone release and collagen synthesis are highest
J Magn Reson