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Administration of intracerebral ventricular phlorizin [43, 44] as well as intracerebral ventricular administration of antisense SGLT1mRNA [45] reduced infarct size and cognitive deficits after medial cerebral artery occlusion (MCAO)
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Although RETA induced a significant reduction in fasted blood glucose concentrations after 1 week, which steadily rose over time but remained significantly reduced compared to Veh, RETA-w/d caused a sharp increase in fasting blood glucose (Fig
Extrapolating those results to a non-diabetic obesity population is speculative
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