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Research-grade chemicals are not meant for human consumption, so patients are left questioning whether quality or authenticity is consistent, which can make it difficult to know whether changes in results are due to the drug, dosing, or the product itself

Step two: adding injectable therapy When metformin alone (or metformin plus other oral agents) fails to achieve blood sugar targets, the next decision is whether to add a GLP-1 agonist or insulin

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Prof Giles Yeo of the University of Cambridge said generic versions will lead to a further boom in use particularly in lower-income countries