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Adenosylmethionine decarboxylase 1 is encoded by the AMD1 gene
Secondary endpoints: GSH concentrations in maternal and arterial and venous umbilical cord blood erythrocytes (by stratification based on treatment or degree of IPTB severity) and safety of antenatal NAC supplementation for mothers and infants Considering stratification for IPTB severity, median glutathione concentration in venous cord blood was similar in severe (median: 430 mol/L) and moderate (median: 402 mol/L) IPTB in the NAC arm ( P 1.0), whereas it was lower, however not significantly ( P 0.67), in severe (median: 391 mol/L) than moderate (median: 522 mol/L) IPTB group in the placebo arm (Supplemental Table S3)
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Cells were incubated with QIs or parent compounds for 2.5 h, based on the time-dependency of QIs-induced loss of cell viability (Supplementary Figure S3)
For this reason, we recommend ongoing sessions
