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Free Radic Biol Med 37:755767 Hirst J, King MS, Pryde KR (2008) The production of reactive oxygen species by complex I
Some people think that supplementing with the building blocks of glutathione, like N-acetyl-cysteine (NAC), helps to make glutathione, but this isnt always true
& Mishra, M
LC reduces pro-oxidant ROS-generating enzymes xanthine-oxidase (XO) and nicotinamide-adenine-dinucleotidephosphate-oxidase (NADPH-oxidase), and chelates metal ions (Fe2 + , Cu +), or acts as a buffer for excessive acetyl groups, that leads to a lower mitochondrial superoxide production [32]
Well, rather than supplementing with folic acid, which would likely accumulate due to a lack of MTHFR to process it, consider an active folate supplement instead that contains methylfolate
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