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It plays an important role in fatty acid metabolism and energy production by facilitating the transport of long-chain fatty acids into the mitochondria, where they are then broken down and converted into energy through beta-oxidation
These agents benefit individuals with atherosclerosis, heart failure, or chronic kidney disease (CKD) (6)
It may strengthen your immune system and relieve oxidative stress prior to travel, life events, or exposure to sick family members or friends
Side effects are broadly similar, with tirzepatide more often linked to nausea and vomiting, and semaglutide more to constipation and reflux
This shift in endpoints reflects a broader reframing of obesity as a chronic disease rather than a lifestyle issue
The dosing requires gradual titration over four weeks, building up to two tablets twice daily
