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Brian Lee, a USC physician who voted no, warned the committee that this would not be an FDA approval but that people would read it as one anyway, and that impression is very hard to undo
Maintenance doses may be recommended based on your ongoing needs
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(2026) Zhu et al
Phase 2 trial (NEJM 2023) reported 24.2% mean weight loss at 48 weeks with 12 mg/week retatrutide, with gastrointestinal adverse events rising sharply at the 8 mg and 12 mg doses
The exact dose may depend on individual needs and should be determined by a medical professional
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