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Bomba M, Granzotto A, Castelli V, Onofrj M, Lattanzio R, Cimini A, et al
They also reduce the risk of side effects and support more predictable results
Fc engineering of human IgG1 for altered binding to the neonatal Fc receptor affects Fc effector functions
However, the risk narrative leans heavily on earlier or animal data while under-playing substantial 202425 human evidence that attenuates many of the red-flag signals
doi:10.1016/j.biopha.2020.110137
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