Activation of 3-AR via Gs cAMP PKA phosphorylation of hormone-sensitive lipase (HSL) leads to: Splitting of triglycerides into free fatty acids + glycerol Release of fatty acids from adipose tissue into the blood Increased oxidation of fatty acids in mitochondria (muscle, liver) Heffernan et al
Acknowledgments The authors would like to thank Pat Kornic and the Pernicious Anaemia/B12 Deficiency Support Group and Tracey Witty and the B12 Info group ( Notes Funding There was no funding for this study
Yes, adverse effects may include pain, redness, or swelling at the injection site
Vitamin B12 therapy offers a practical advantage
StatPearls [Internet], 2023 June Takaaki Sugihara, Masahiko Koda, Toshiaki Okamoto, Kenichi Miyoshi, Tomomitsu Matono, Kenji Oyama, Keiko Hosho, Jun-ichi Okano, Hajime Isomoto, Yoshikazu Murawaki
Improves energy metabolism to ensure the efficient release of energy necessary for optimal muscle function and optimal oxygen carrying capacity of red blood cells for muscle perfusion