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Sources: Boehringer Ingelheim release | Zealand Pharma announcement | PharmaTimes coverage | BioPharma Dive analysis
All authors contributed to manuscript revision, read, and approved the submitted version
15 , e1007889 (2019)
JOE ROGAN: Of surface and deep
The protocol: Reduce sulfonylurea dose by 50% when starting semaglutide Monitor blood glucose before meals and at bedtime for 2 weeks Many patients discontinue sulfonylureas entirely within 4 to 8 weeks as semaglutide reaches therapeutic levels The SUSTAIN-2 trial (Ahrn et al., Diabetes Care , 2018) showed that 41% of patients on sulfonylureas plus semaglutide experienced hypoglycemia, compared to 11% on semaglutide alone
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