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Both contain the same active pharmaceutical ingredient and work through identical mechanisms: reducing appetite by activating GLP-1 receptors and improving blood sugar control

The other drug currently involved in the Ozempic lawsuit, Mounjaro, is manufactured by Eli Lilly and Company

Finally, FGF21 reduces expression and activation of the NLRP3 inflammasome in vascular endothelial cells in diabetic mice (184), which both protects the cells themselves and reduces further inflammatory damage by suppressing pyroptosis and immune cell recruitment (185)

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10.1038/npp.2015.73 131

Those taking higher doses typically lost more weight than those taking lower doses