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The receptor for GLP-1 is the GLP-1 receptor (GLP1R), a G-protein-coupled receptor
Invest 124 , 44734488 (2014)
Besides, participants saw significant improvements in cholesterol, blood pressure, blood sugar levels, and triglyceride reduction
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Conversely, downregulation of CHAC1/BOTCH was associated with increased neuronal damage and impaired recovery ( The regulation of CHAC1/BOTCH involves additional molecular players: during intracerebral hemorrhage, inhibition of CHAC1/BOTCH by the androgen receptor (AR) and Jumonji-domain containing protein-3 (JMJD3) led to elevated NOTCH1 levels and exacerbated neuroinflammation ( ATF4 was most prominently upregulated, though other related genes were also significantly elevated (Yasuda et al., 2014)
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