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Graille, M., Chaillet, M

*Correspondence: Qing-Rong Xia [email protected] This article was submitted to Mood and Anxiety Disorders, a section of the journal Frontiers in Psychiatry Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

Although the mechanism of EE/ICA remained obscured, a recent study showing that icaritin, a major intestinal metabolite of ICA, activated the phosphatidylinositol 3 kinase (PI3K)/AKT/FoxO signaling pathway in C2C12 myoblasts 33 , in along with that ICA treatment activated insulin receptor substrate-1 (IRS-1) and AMP-activated protein kinase (AMPK) signal pathways to improve insulin resistance in skeletal muscle cells 34 suggest that the IGF-1/AKT pathway activation may play a critical role in the aforementioned effects of EE/ICA

Even processed foods with artificial additives contribute

For a 1:1 combo, every draw contains equal parts of both compounds

The amount of air should be equal to the prescribed dose of B12