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A randomized pilot clinical trial of the safety of pioglitazone in treatment of patients with Alzheimer disease

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Wang T, Lu W, Tang H, Buse JB, Strmer T, Gower EW

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However, more patients dropped out due to serious side effects, which would be a major problem for frail elderly patients who already have trouble tolerating medications

By getting a B-12 shot you can bypass the stomach entirely and it can be absorbed directly into the bloodstream