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Regarding metabolic parameters, Cagrilintide treatment did not produce significant changes in HbA1c or fasting plasma glucose from baseline to week 26, while liraglutide 3.0 mg significantly improved both measures, consistent with its known glucose-lowering effects

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"This is the first instance where we've seen that semaglutide 2.4 mg enhances cardiovascular outcomes in high-risk patients with a BMI of 27 and above, who have established CVD but do not have diabetes," stated Dr Michael Lincoff, the study's principal author and vice chair for research at Cleveland Clinic's Cardiovascular Medicine Department

Spearmans correlation was performed for analysis between the quantitative covariates and the outcome

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