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These uses may have the backing of plausible mechanistic rationales, but none possess the robust clinical validation I would want to see in a proven protocol
In studies with adult female rats injected with methylprednisolone (a glucocorticoid), simultaneous administration of ipamorelin 100 g/kg three times daily for 3 months significantly increased maximum tetanic tension of calf muscles compared to the glucocorticoid-only group
(PubMed) Zhou H, Wang T, Li Q, Li D
Key Takeaways Peripheral artery disease (PAD) affects 8-12 million Americans and causes leg coldness by reducing blood flow through narrowed arteriesankle-brachial index below 0.9 indicates significant blockage
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