Bupropion-naltrexone (Contrave): Its a combination of two drugs: bupropion which reduces appetite and naltrexone which controls cravings
- Use lithium as the basic treatment, specifically for bipolar disorder type 1, and combine with: - Quetiapine (best evidence), depending on the patients risk of cardiovascular disease and metabolic risk profile, use the following alternatives: lurasidone, cariprazine - Lamotrigine may be considered when lithium or antipsychotics are unsuitable
Across published clinical trial work, researchers have studied it for weight management, weight reduction, body composition, fat loss, appetite suppression, and broader metabolic regulation, with reported doses up to 12mg by subcutaneous injection
Im a clinical professor of psychiatry at the Icahn School of Medicine at Mount Sinai in New York
6 months, 9.5% vs
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