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All experimental procedures complied with relevant ethical standards and guidelines

Signalling pathways studied in preclinical models illustrative Melanocyte Stimulation & Pigmentation MC1R Agonism Melanotan II (MTII) activates MC1R on melanocytes, stimulating intracellular cAMP production that drives melanogenesis the synthesis of eumelanin (brown-black) pigment

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However, in another study asthma patients (ages 15-45) receiving oral choline supplementation (1500 mg b.i.d.) with inhaled steroids (Budesonide

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