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To further investigate the role of gut microbiota, the researchers induced early-life gut microbiota perturbation through a short-term antibiotic treatment administered from postnatal day 16 to day 22, and sacrificed the mice at 40 weeks of age
Front Neuroendocrinol (2016) 42:7692
NICE advises continuing treatment only if there is a clinically meaningful HbA1c reduction (for example 11 mmol/mol [1%]) and weight loss of at least 3% of initial body weight
EP45 exhibited true GLP-1R specificity since it exerted no effect when tested at 1,000 nM in HEK293 cells that stably expressed rat glucagon or rat GIP receptors (Fig
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